How is PFO closure performed?

PFO closure is performed in the hospital. The devices are implanted via the large vein in the groin, and an ultrasound camera in the other large vein in the groin provides guidance. Most people go home the same day, and the procedure is usually very well tolerated. It is done under sedation. Patients will need to be on aspirin and a second blood thinner for at least a month and then on aspirin indefinitely.